Prognostic value of cellular proliferation and histologic grade in follicular lymphoma

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Prognostic value of cellular proliferation and histologic grade in follicular lymphoma.

The clinical usefulness of histologic grading in follicular lymphoma (FL) is controversial and is further compromised by the subjective nature and poor reproducibility of most systems in current use. Therefore, we decided to objectively evaluate the importance of cellular proliferation in FL, along with the current grading systems. We studied 106 patients with FL who were uniformly staged and a...

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The t(14;18)(q32;q21) chromosomal translocation is observed in more than 75% of cases of follicular lymphoma. Several additional chromosomal abnormalities, which might contribute to tumor progression, have also been described. However, prognostic implications of cytogenetic features in follicular lymphoma have not been clearly established. In an attempt to correlate cytogenetic findings with cl...

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Prognostic factors in follicular lymphoma.

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ژورنال

عنوان ژورنال: Blood

سال: 1995

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v85.12.3671.bloodjournal85123671